Giáo sư khùng II: Gia đình Klump

Eddie Murphy

Sherman Klump / Buddy Love / Granny Klump / Mama Klump / Papa Klump / Young Papa Klump / Ernie Klump / Lance Perkins

Janet Jackson

Denise

Larry Miller

Dean Richmond

John Ales

Jason

Richard Gant

Denise's Father

Anna Maria Horsford

Denise's Mother

Melinda McGraw

Leanne Guilford

Jamal Mixon

Ernie Klump, Jr.